Our team is a multidisciplinary UK national alliance of doctors who are collaborating with researchers in Dublin, the NIH (Washington) and Europe.
Dr Ramesh Bulusu - Our Clinical Lead
Consultant Clinical Oncologist MD, MRCP, MSc, FRCR (Oncology)
Dr Bulusu is the alliance lead and one of the national experts on gastrointestinal stromal tumours (GIST). Working with other specialists in this area, he has developed the national guidelines for the management of this tumour and has lectured, presented and published extensively on the subject.
He is actively involved in numerous clinical trials as a principal and co investigator and has been the consultant clinical lead for PAWS-GIST since its inception in November 2010.
Dr Michael Leahy
Consultant Clinical Oncologist - BSc (Hons), MBBS, PhD, FRCP
Dr Michael Leahy attended medical school in London and trained in oncology at the Royal London Hospital and St Bartholomew's before completing his specialist training at The Christie, Manchester, in 1998. He spent six years at the University of Leeds as senior lecturer in medical oncology and is now based in Manchester as a medical oncologist on the supra-regional sarcoma and testicular cancer multi-disciplinary teams. Dr Leahy has worked with the PAWS-GIST Alliance since its inception.
Dr Beatrice Seddon
Consultant Clinical Oncologist
Dr Beatrice Seddon is Consultant Clinical Oncologist on the Sarcoma Unit at University College Hospital, UCLH NHS Trust, specialising exclusively in the management (chemotherapy and radiotherapy) of soft tissue and bone sarcomas. Dr Seddon trained in sarcoma oncology at the Middlesex Hospital and the Royal Marsden Hospital. She currently lectures and teaches on the management of sarcomas, and is actively involved in clinical research projects in this area. She is a member of the EORTC Soft Tissue and Bone Sarcoma Group and the NCRN Sarcoma Group.
Dr Julia Chisholm
Consultant Paediatric Oncologist, MA (Cantab), PhD (Cantab), BMBCh (Oxon), FRCPCH
Dr Julia Chisholm is a Consultant Paediatric Oncologist. Currently Head of the Paediatrics Unit at the Royal Marsden..
Dr Chisholm joined the team at The Royal Marsden to lead the development of the new teenage and young adult service. She has a specialist practice in soft tissue sarcoma in children and young people, working closely with members of the adult Sarcoma Unit, and is an integral member of the children and young people�s drug development team.
She is a member of the European Innovative Therapies for Children with Cancer clinical network, and she chairs the Phase II Committee of the European Paediatric Soft Tissue Sarcoma Group. She has a particular focus on drug development for soft tissue sarcomas in children and young people and is chief investigator on several phase I and II paediatric trials. She has published widely on soft tissue sarcoma, early phase studies and supportive care.
Dr Newton Wong
Consultant Histopathologist - BSc MRCP , MBChB, FRCPath, MD
Areas of interest:
- Molecular diagnostics;
- Gastrointestinal pathology;
Dr Shaun Walsh
Prof Maureen O'Sullivan
OLCHC MB BSc PhD
Consultant Paediatric Pathologist, Our Lady's Children's Hospital, Crumlin, Dublin and Clinical Professor, Department of Histopathology, Trinity College, Dublin, IRELAND.
The focus of research in my group is genetics and epigenetics of solid pediatric tumors, notably sarcomas and renal tumors. One aspect of investigation is the characterization of novel chromosomal translocations in these tumor types. Through our improved understanding of such genetic aberrations in other tumors, including leukaemias, there have been very significant strides in improved treatment in children with leukaemia. Our aim is to unravel the genetic aberrations that govern sarcomagenesis with an aim of similar end-effect.
Professor Andrew Hall
- Director, Northern Institute for Cancer Research
- Director, Newcastle Biomedicine Biobank
- Designated Individual for Human Tissue Act Research Licence for Newcastle University
- Professor of Experimental Haematology
- Honorary Consultant Haematologist, Newcastle upon Tyne NHS Foundation Trust
- Pathology Lead, NCRI Confederation of Cancer Biobanks
Professor Hall has been instrumental in setting up of the National GIST tumour bank.
Professor Ian Judson
- FRCP, Royal College of Physicians, London
- MD, University of Cambridge
- BA (Hons), Natural Sciences, Univesity of Cambridge
- MB, BChir,, University of Cambridge
Professor Judson has specialised in the management of sarcomas for the past 20 years and has made a particular study of gastrointestinal stromal tumours (GIST). He was a principal investigator in the Phase I/II trial of imatinib for GIST in 2000/1 and has been actively involved in research into the treatment of this disease since that time.
Dr David Gonzalez de Castro
PhD Molecular Genetics
Dr David González de Castro is a Consultant Clinical Scientist and Head of the Molecular Diagnostics department at The Royal Marsden Hospital and The Institute of Cancer Research.
Dr Nicholas Carroll
Consultant Radiologist and Endoscopist, Addenbrooke's Hospital NHS Trust, Cambridge
Special clinical interests: Gastro-intestinal imaging and Endoscopic Ultrasound
- Member of the European Society of Gastro-intestinal and Abdominal Imaging
- Fellow of the Royal College of Radiologists
- Pioneered the development and use of EUS in the eastern region of the UK and currently secretary of the national EUS body.
Mr Richard Hardwick
Specialist Upper Gastro-Intestinal Tract Surgeon
Specialist upper gastro-intestinal tract surgeon with an interest in keyhole and hiatus hernia surgery and gastric and oesophageal cancer. Lead clinician for upper GI cancer at the Cambridge Oesophago-Gastric Centre, which he co-founded in 2001, lead for the National Oesophago-Gastric Cancer Audit and past chairman of the Association of Upper GI Surgeons Audit and Clinical Services Committee. Research interests include early diagnosis of upper GI cancer, Barrett's oesophagus and hereditary forms of stomach cancer. A vociferous campaigner for improved NHS resources.
Mr Simon Toh
Consultant Surgeon at Portsmouth Hospitals NHS Trust
Experienced innovative general surgeon keen on latest innovations to improve surgical treatments for cancer and benign conditions. Developing training centre of excellence in robotic surgery in Portsmouth.
Dr Phillippe Tanniere
Consultant in Histopathology
Dr Phillippe Tanniere Consultant in Histopathology at the Queen Elizabeth Hospital and Honorary Senior Lecturer at the Medical School, Birmingham, with a special interest in gastro-intestinal and pancreatico-biliary pathology.
Dr Denise Williams
Consultant Paediatric Oncologist - MB Bch (Wales) FRCP FRCPCH
Dr Denise Williams is a specialist in children's cancer care and manages all types of solid tumours as well as working closely with haematology colleagues in the management of children with leukaemia. Her main clinical and research interest is in lymphomas in children and she chairs the European Intergroup Collaboration for paediatric non-Hodgkins Lymphoma (EICNHL).
Dr Palma Dileo
Dr Palma Dileo is Consultant Medical Oncologist on the Sarcoma Unit at University College Hospital, UCLH NHS Trust, specialising exclusively in the management (chemotherapy and radiotherapy) of soft tissue and bone sarcomas. The Sarcoma Unit at UCLH, together with the Sarcoma Unit at the Royal National Orthopaedic Hospital, is the London Sarcoma Service (www.londonsarcoma.org) which offers a comprehensive clinical service to patients of all ages with sarcoma at all sites of the body. She has continued to provide patient care since 1996 (general oncology), with more emphasis on sarcoma and rare tumors starting from 1998. She completed her training at the Istituto Nazionale Tumori of Milan, Italy and at Dana-Farber Cancer Institute, Boston, USA. From 2006 to 2010 she has been Associate Physician, Medical Oncology, Istituto Nazionale Tumori, Milan working in the Sarcoma Team. She has a strong interest in early phase clinical trials and is a co-investigator for a number of clinical trials in sarcoma. She is a member of the EORTC Soft Tissue and Bone Sarcoma Group and ASCO.
Professor Eamonn Maher
Eamonn Maher is Professor of Medical Genetics and Genomic Medicine and Head of the Department of Medical Genetics. Prior to taking up this post in 2013 he was Professor of Medical Genetics and Academic Lead for the Centre for Rare Diseases and Personalised Medicine at the University of Birmingham. Eamonn has published around 400 research papers in scientific journals as well as reviews and book chapters in the fields of cancer genetics, human developmental genetics, epigenetics and genomic imprinting. He has a particular interest in research training for clinician and non-clinician scientists and had supervised more than 25 PhD or MD students to completion. Current research in Eamonn’s group relates to the molecular basis of inherited forms of renal cell carcinoma (supported by an ERC Advanced Researcher Award 2013-2018), phaeochromocytoma, multiple primary cancers, genomic imprinting disorders (www.ingenium-itn.eu) and developmental disorders.
Dr Robin Jones
Dr Robin Jones is a medical oncologist specialising in the treatment of bone and soft tissue sarcomas. He has experience in conducting Phase I, II and III trials, as well translational studies in sarcoma. He trained in medical oncology at the Royal Marsden Hospital and between 2010 and 2014 he was Head of the Sarcoma Program at the University of Washington / Fred Hutchinson Cancer Research Center in Seattle. His main research interest focuses on clinical trials of novel agents and immunotherapy in sarcoma.
Dr Charlotte Benson
Dr Charlotte Benson is a Consultant Medical Oncologist working at the Royal Marsden Hospital Sarcoma unit. She specialises solely in the treatment of Soft tissue Sarcoma and GIST. She is active in research and is a member of the EORTC Soft Tissue Sarcoma and Bone group and the NCRI Sarcoma CSG.
Dr Olivier Giger - MD, PhD, University Lecturer and Honorary NHS Consultant
Dr Giger completed his me dical and speciality training in Switzerland and was awarded an MD at the Univeristy of Zurich. He received a PhD from the University of Liverpool for his research on epigenetic changes in the tumour stroma. He is now a University Lecturer and Honorary Consultant in Molecular- and Histopathology working in the Department of Pathology and the Haematopathology & Oncology Diagnostic Service (HODS) at Addenbrookes’ University Hospital in Cambridge.His area of expertise lies in gastrointestinal pathology and molecular pathology of solid tumours. His research interests include the tumourmicroenvironment, gastrointestinal stromal tumours and colorectal cancer. He also enjoys teaching undergraduate and postgraduate students.
Dr Ruth Casey MB BCH BAO, FRCPI
Dr Ruth Casey is currently in the final stages of her PhD and is due to take up a consultant post in Endocrinology in Cambridge University NHS Foundation Trust in September 2018. Dr Casey has a specialist clinical interest in hereditary endocrine neoplasia and endocrine cancer. Her research has focused mainly on the role of succinate dehydrogenase gene mutations in tumorigenesis and has a strong translational focus. Her interest in succinate dehydrogenase deficient tumours has led to her collaboration with PAWS GIST.
Supporting / Associate Bodies & Individuals
- GIST Support UK:
Life President - Judith Robinson, Chair - Nic Puntis
- SPAEN - Sarcoma Patients Euronet:
Roger Wilson & Marcus Wartenburg
- Paediatric & Wild-type GIST Clinic NIH Washington USA:
Dr Lee Henman - Pediatric Oncologist, Scientific Director of Clinical Washington DC
PAWS-GIST Patient Director, Vice Chair & Trustee GIST Support UK: Jayne Bressington
Patron: Charlie Hamilton James
Wildlife Photographer and television presenter
Fundraising, Social Media & Trustee GIST Support UK: Dr Victoria Bassett